Enhancing GI infection outcomes through
early identification.

Gastrointestinal infections (GIs) in both pediatric and adult patients account for significant morbidity and mortality (CDC publication 1 and 2; Schlenker C and Surawicz CM, 2009). Mortality in neonatal (3%) and <5 years children (17%) is attributable to diarrhea (Fisher et al., 2010; Patel et al., 2010). Bacteria, viruses, and parasites cause Gastrointestinal Infections (GIs) in Humans. More than 200 million GIs occur annually in the United States. Traditionally, less sensitive classical detection methods (e.g., culture, antigen Enzyme-immunoassays, stool parasite microscopy) have been used to identify the causative agent of GIs. Rapid diagnosis is important for appropriate treatment and infection control measures and mortality.

GenviewDx lab offers a sensitive nucleic acid-based PCR test intended for the simultaneous detection and identification of multiple viral, parasitic, and bacterial (collectively called Gastrointestinal Pathogen Panel) in human stool specimens from individuals with signs and symptoms of infectious colitis or gastroenteritis. The Gastrointestinal Pathogen Panel consists of 7 different viruses including their subtypes (a total of 14 viruses), 17 bacteria (22 with species), and 6 parasites (9 with species). This GI panel consists of a total of 45 pathogens.

Signs, symptoms, or circumstances to order GI test: 

  • Acute or chronic diarrhea with or without blood of any age.
  • Returned traveler with or without immunocompromised status.
  • Hospitalized patient with outbreak identification in healthcare settings and in specific populations (newborns/infants, elderly) as these infections are potentially serious.

Benefits of GenviewDx lab’s GI PCR Test:  

  • A nucleic acid-based PCR test: Highest sensitivity and specificity for detection of the common enteric pathogens (32 pathogens; bacteria, viruses, and parasites).
  • Faster diagnosis of gastrointestinal infections (within 24-hour of turnaround time after receiving the sample to the lab).
  • Submit stool specimens in sterile containers with no transport medium required.
  • Multiple or co-infections will be determined by one multi-pathogen panel without delay for repeat tests.
  • With 1-2 mL of stool sample is enough to evaluate multiple pathogens.
  • Board-certified technologists to answer your questions 24/7. 
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Gastrointestinal Infection Pathogen Panel

References
1. Centers for Disease Control and Prevention (CDC). Risk Factors for Foodborne Illness.
2. Centers for Disease Control and Prevention (CDC). Scallan, E. et al. Estimated Illnesses and Deaths Caused by Foodborne Pathogens.
3. Schlenker C, Surawicz CM. Emerging infections of the gastrointestinal tract. Best Practice & Research Clinical Gastroenterology. 2009;23(1):89-99.
4. Fischer Walker CL, Sack D, Black RE. Etiology of diarrhea in older children, adolescents, and adults: a systematic review. PLoS Neglected Tropical Diseases. 2010 Aug 3;4(8).
5. Patel A, Mamtani M, Dibley MJ, Badhoniya N, Kulkarni H. Therapeutic value of zinc supplementation in acute and persistent diarrhea: a systematic review. PLoS One. 2010 Apr.